Tyre wise, there needs to be a big change. Pirelli have supposedly signed a new contract to be the sole supplier of tyres for F1 for the next 5 years... (Source:Pirelli reportedly agree a new five-year deal to continue as F1's sole tyre supplier | Sky Sports)
If this is true I hope the tyres are made to last a lot longer than current tyres, like you say whats the point in holding off to prevent tyre wear!! It's become more about tactics instead of wheel to wheel racing...
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Fuel, wheel, can't see them going back to the days of fueling during the race...