It's an interesting discussion to have. In what way would you for-see the ability to spoof changing between v4 and v6 though? It's very hard to genuinely spoof addresses over the Internet (if you want to receive the return traffic back, which you'd need for the likes of TCP sessions for spamming etc). If however by spoofing you mean the use of anonymous Internet proxies, I don't see how that situation changes between v4 and v6? If anything, I'd see that getting rid of NAT should make combating spammers etc easier, as by ACLing or cutting off certain IP addresses, you don't run the risk of cutting off a NAT/proxy/service box and thus affecting the connectivity/services of a huge number of users.
Rob