[ms office - o365] Click to run outlook not opening

[HereIGoAgain2601]

We are seeing an intermittent issue across sites with office 365 click to run. Randomly when trying to launch the Outlook client the 'click to run' software update/repair orange screen will boot up instead. It will try and do something and fail. It then gets stuck in a loop doing this. If we restart click to run service Outlook loads fine and then continues to work for several days.

 

The issue then repeats intermittently. Does anyone have any ideas?

 

Checked the obvious e.g. installing client updates, given machine full outbound firewall / web and still the issue persists.

 

Thanks