This message is indicative of a likely issue in your disk subsystem. This event comes from some new functionality built into the Windows 8 / Server 2012 and newer versions of ESENT to detect lost flushes during runtime (but not during boot, crash, power outage, etc - those are still completely undetected until you hit the corruption with applications or newer operating systems). Lost flushes are very bad and cause corruption in the Active Directory Database. This type of corruption is the most insidious type of corruption as it causes unknown divergence, index corruption, bad page links, and uninitialized AD/LDAP failures that may not show up for even months down the road and then suddenly jump out at you when implementing new functionality (new versions of Exchange are great for finding corruption) or bringing in newer OS Domain Controllers that prevent you from moving forward in your deployments. Translation, you could get corruption that isn't detected until AFTER all of your backups are compromised.
Anytime you make the path from the CPU to the bits on the storage medium more complex (such as virtualization, SANs, complex RAID configurations, complex caching hardware/software, data deduplication, etc) you raise the overall risk for corruption to occur. It is absolutely essential to the overall health of your Directory to catch these failures and remediate the underlying platform issues ASAP when encountered and hope that the corruption hasn't replicated to the rest of your environment.
Unfortunately at this time (and probably not anytime in the near future), it is not possible to authoritatively scan an Active Directory Database and find all forms of corruption. If you perform various ESENTUTL commands you may or may not find corruption that exists. You may or may not be able to repair it if you find it. Keep in mind corruption can range from high level unimportant stuff like a description being changed to odd characters that can be corrected with a simple LDAP update to deep table level corruption that cannot be corrected in any way.
joe