Hi Andyturple,
Assuming your users have home areas assigned to them on a separate file server or some sort of storage, you can configure your Macs to save to their home areas. This can be done by doing the following System Preferences > Users & Groups > Login Options > Edit (Network Account Server) > Select your AD Server > Open Directory Utility > Active Directory > Untick Force local home directory on startup disk. This should hopefully do what you are looking for.
Shaun