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Thanks Synack Yes the workaround is to delete users profile on the new terminal servers. This works and resolves the issue. However this is a temporary workaround, and getting tiring for the 1200 users that logon to citrix. There’s something under the HKCU users profile causing the error. I’ve googled and done the recommended suggestions without success. ie Delete specific User keys Delete registry keys Delete Words data key HKEY_CURRENT_USER\Software\Microsoft\Office\12.0\Word\Data Delete Word Options key HKEY_CURRENT_USER\Software\Microsoft\Office\12.0\Word\Options Perform an Office repair under user. Perform an Office diagnostic under use Uncheck Compatibility Mode and Privilege Level. "Run as administrator". The checkbox isn't ticked in winword.exe's properties Change Shell Open command and remove the DDE switch from line "C:\Program Files\Microsoft Office\Office12\WINWORD.EXE" /n /dde The result: works however each time you double click a word doc launches a second (additional) Word sessions Also other software reliant on the DDE no longer works and has integration. Change printer drivers

hello Norphy I’m experiencing the same issue except in Word 2007. I’ve implementedthe same suggestions however the error persists. Environment: Terminal servers Citrix server - Xenapps 6.0 on Win 200764bit Office 2007 SP3 Issue: From the desktop users double click on a word document. The result is a message displays "There wasa problem sending the command to the program". Word opens, however the document doesn’t. Occurs first time on Word start-up within that session. If Word is already open the message doesn’t display. All other applications ie Excel, PowerPoint behave correctly. Did the Microsoft hotfix resolve your excel issue on Cheers,