I have an Acer Aspire One running Ubuntu and it all works out of the box so to speak appart from the card readers. Is the version of Ubuntu going to be the normal version or the Netbook Remix. I would recomend the Netbook version, if that is the case then the card readers will work if you have a card plugged in at boot. after boot they are hot swappable. you can get a live CD of ubuntu that will let you boot and run Ubuntu from the disk so you can try it out without changing anything on the drive.
