You have two network cards on the DC, try disabling one and test the connection to the File server N drive. If that works, disable the other and try the same thing.
If they both work, perhaps it's a problem with your teaming configuration. If one works and the other doesn't, replace the NIC that didn't work and team again.
If neither works, then try pinging the loop back 127.0.0.1 whicle each of NIC's are disabled. If that works then it may be something outside the server side. Perhaps the network cable, a hub or switch if there is one between the DC and the file server.