I moved from Sophos to Nod and managed to get it running after a struggle and now its pretty good.
heres what I found works for me
* the update web server needs to be moved onto its own IIS, the in built one is useless for a bigger network
* I never install via the console.. since I upgraded the console the new layout is awful so all I do is go to the computer and run a batch file tha runs the MSI silently. All new computers automatically get a default profile which updates it.
I almost changed back to Sophos but the cleaning and protection seems alot nicer in NOD so I am sticking with it... I really miss the simple console of Sophos.
Also here after initial setup problems works like dream on x64 and x32, only problem I see is that sometimes it won't update until you reboot. Oh and you must turn off scan network drives on the client or it will try scanning massive areas, well thats if you have say a mapped drive to a public documents folder that is very big. I can also say that since we got it two years ago we have not had a serious virus attack, it finds plenty and deals with them.
Yes it does come as an MSI, but I'm unable to fathom how I configure nod to look for my central admin server. if you deploy the MSI as is, it has no licence, no schedule, and isn't setup to look for central control. I couldn't find away of setting up an MST to send off with it. As for the technical support it was about 2 years ago with ping ponging my problems and being told that what I was experiencing wasn't possible, I decided that mostly working was better for my sanity than exploring a fix.
You put the config file in the same directory as the MSI and then it installs with the settings you want, finds your server, and then takes additional settings / config changes from it. I've never had to push anything and i've had no problems although I've only been using this since the summer. Whenever I've spoken to support they are usually pretty switched on and talked me through most things.
You are at queue position 1 in the queue :)
Sorted lovely support man gave me instructions on how to download my licence file from their webserver as live@edu had stripped the attachment out.
Why they can't include that with the email originally in case that happens I do not know.
For those struggling with NOD32, this thread from a few months ago turned in to a general NOD32 trouble-shooting discussion.