Brand new Active Directory - From scratch
We are going to be installing a brand new Active Directory environment. This will be based on Windows Server 2012 R2 domain controllers (all virtualized under ESXi/vSphere), and hopefully all clients will be Windows 7+. We will still have all of the data from staff/student home drives, along with things in shared areas, but these will need to be copied and sorted out on a new file server.
What I'm interested in is how others currently have their AD set up - and, if they were able to recreate it from scratch, what they might do differently. This includes everything from how domain controllers are configured, through to OU structure, groups, NTFS permissions, Group Policy, etc.