Fix: Office2007 (Publisher) Lock up
Had this one with Publisher 2007 and it's been driving me slightly potty for the last 3 months...
Start up Publisher 2007 using the shortcut (ie: not by opening an existing document) and the Publisher program window goes blank. In some cases (like mine) it also locks up explorer and you can't CTRL+ALT+DEL to task manager to kill it. (Good ole' Microsoft fubaring their own OS!).
Note: This also happens if you open Publisher by opening it through a specific *.pub document but then try File > New.
It seems that usually this indicates that the default printer for your PC is not configured properly, ie: corrupt driver, unavailable or something. In my case it's a K5400 which works just fine but Publisher doesn't like it.
Select a different printer as the default before you start up Publisher.
For good measure I deleted inactive printers and cleared the recently open files list in registry too.