Default Download location reset to C:\ so in User Configuration/Preferences/Windows Settings/Registry/ add new
HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer, Right Pane Select Default Download location, update to (User Home Drive)

EasyMail+ will not reply to messages in IE9, so enable
Computer Configuration/Administrative Templates/Windows Components/Internet Explorer/Compatibility View

Sorry if I'm telling any of you what you already know, but I've just had to search these out...