We have just bought 20 odd of these and a Parasync Docking Station. The dock is expensive (around £1K) but it charges them all and connects up to itunes to sync them all simultaneously
I'm using itunes and iphone config util, it works but it's a lot of pain cancelling pop ups etc in itunes
and I haven't found a way to remove default apps yet, (or bulk re arrange screens) so they are all just shoved in a folder and put on another screen out of the way
setting up a profile in iphone config util restricts most things
If you're using a PC not a mac if find that itunes / config util locks up after I have more than 14 connected at a time - told it's to do with USB hardware
Also the PC version of itunes does not allow you to choose to sync all at once. it does however sync automatically when you plug them in tho
(You can choose what gets synced when they are plugged in on first set up)
Our school did not want to attach a credit card to an itunes account for apps so we got a gift card. There is a way to set up an itunes account without a credit card as long as you try to buy a free app first before you have an account, search the apple website for the guide
I think it would be worth trying setting one up first and then cloning all others from this one...
You can restore ipods from backups made automatically by itunes. On first set up you get the option to choose to restore it from a backup you specify
I haven't tried this yet but it makes more sense to me considering the management tools are hardly what i would call 'enterprise'
Another consideration is security marking... they are small and polished, the standard ink kit rubbed straight off, I had to get an engraver and scratch it in with a stencil. There is a tracking service you can sign up to, I haven't got that far yet and suspect it's very personalised which is not ideal for a school. Still if you could sign into a website and say 'there's our missing ipod' call the cops and i'll put the kettle on it would be worth it lol
All in they are a lot of work to set up and I haven't been able to restrict them as much as i would like, but obviously we hope they will have a really big impact
Would like to know how you get on and what you do with them

we are starting out with maths apps and reinforcement of basic skills, but looking forward to doing more intereting stuff.
Cheers!
L