Stanford Online Courses
Stanford's new online courses that follow the same syllabus as their on site courses.
"Students will have access to lecture videos, lecture notes, receive regular feedback on progress, and receive answers to questions. When you successfully complete the class, you will also receive a statement of accomplishment."
Introduction to Databases - Stanford University
Machine Learning - Stanford University
Stanford School of Engineering - Stanford Engineering Everywhere
I've done a fair few open online courses from several US Establishments
Yale, Stanford and MIT (looking at some from Harvard and Princeton as well). Great stuff they are :)